In an era of limited resources, there is a need to use as many byproducts as possible to not only reduce cost but assist in balancing the nutritional profile of the feed. Hydrolyz ed feather meal is a high-protein by-product, rich in sulfur-containing amino acids. If used in low animal meal diets, it can serve as an inexpensive source of amino acids , which contributes to decreasing the cost of production. The present study evaluates the use of various hydrolyzed feather meals as partial substitute to soybean meal in Litopenaeus vannamei diets. Eight isonitrogenous (35% protein) and isolipidic (5% lipid) diets were formulated. The basal diet includes 6% fishmeal and 49% soybean meal as proteins sources. The remaining seven diets were modifications of the basal diet, with hydrolyzed feathermeal with coagulated chicken blood ( HFM-CCB; River Valley Ingredients, Tyson Food Inc. ) or without blood ( HFM-A; River Valley Ingredients, Tyson Food Inc ) partially replacing soybean meal at 3, 6, and 9%, and another hydrolyzed feathermeal without coagulated chicken blood ( HFM-B; Riv er Valley Ingredients, Tyson Foods Inc. ) replacing soybean meal at 6%. Fifteen juvenile L. vannamei were stocked in each of the 32 tanks of an indoors recirculating aquaculture system . Diets were randomly assigned to four replicate tanks . The experiment was performed for 42 days, during which the shrimp were offered feed manually four times throughout the day, and the feed ration adjusted on a weekly basis after shrimp count and survival assessment. The feed ration was based on a standard feeding protocol of the laboratory that assumes the shrimp will double in weight until 0.8g is reached, then will grow by 0.8g per week for the rest of the experiment. The expected FCR used in the present experiment was 1.8. At termination, shrimp were counted and group weighed to assess survival, growth, and FCR. Subsequently, four shrimp from each tank were preserved and later analyzed for whole body proximate composition. Results of the present study suggest that up to 9% of soybean meal can be replaced with hydrolyzed feathermeal (with or without coagulated blood) without significant effects on shrimp growth or survival. Shrimp offered the various diets had an average final individual weight of 5. 60g, and the overall survival among treatments was around 81%. However, significant yet limited differences were observed in terms of FCR and apparent net protein retention among treatments (p <0.05). Shrimp offered the 9% HFM-CCB diet had a significantly bigger FCR ( 1.47) than other shrimp offered the remaining diets. Shrimp offered 3% HFM-A diet had the smallest FCR among treatments (1.30). Similarly, shrimp offered the 9% HFM-CCB diet retained significantly less protein than the remaining shrimp (ANPR = 31.01%). Hydrolyzed feathermeal can serve as an inexpensive nutritious ingredient for shrimp diets. Low animal protein s hrimp diets formulated with hydrolyzed feathermeal ensure good shrimp growth by providing essential amino acids without the need for supplementation.