This study was conducted to investigate the effects of solvent-extracted- soybean meal (SBM), enzyme-treated soybean meal (ESBM) and corn-fermented protein (CFP) meal in the diets on the growth performance, body composition and blood chemistry of grow-out stage channel catfish (Ictalurus punctatus) culturing in pond raceways system. Three ingredients were formulated into three isonitrogenous (32%) and isolipidic (6%) test diets. The basal diet contained 49% SBM as the primary protein source. The second diet (ESBM) utilized enzyme-treated soybean meal as a replacement for SBM, and the third diet (CFP) was supplemented with 10% corn-fermented protein as a partial replacement for SBM. Channel catfish (102.9± 1.8g mean weight) were randomly assigned to 12 raceways (11ft x 4 ft x 4.5ft each) housed in a 1-acre pond. The fish were hand-fed to near satiation once a day. After the feeding trial for four months, no significant differences were found in weight gain(g), weight gain (%), feed conversion ratio (FCR), apparent net protein retention (ANPR), condition factor and survival rate between the channel catfish fed the three diets, but there did seem to be a trend towards an increase in weight gain of fish fed with ESBM diet and CFP diet. Channel catfish fed the ESBM diet have the lowest FCR and highest ANPR than those fed basal and CFP diets. However, fish fed ESBM diet were found to have significantly higher hepatosomatic index (HSI) value and intraperitoneal fat (IPF) value than those fed the basal and CFP diets. Blood chemistry, data will be discussed in the presentation. The results suggest that using enzyme-treated soybean meal as a primary source or including 10% corn-fermented protein to the diet, are both acceptable ingredients that can be utilized in production diets for channel catfish.