Virginia’s shellfish aquaculture industry has a rich history, playing a vital role in the state’s coastal economy. However, unlike traditional agriculture and commodity markets, historical time series data is rarely utilized to document the industry’s evolution. This review seeks to bridge that gap by utilizing the limited data available to provide historical context on landings and sales. Key economic and environmental events that have shaped the industry over time will be analyzed, highlighting their impact on production and market trends. A central focus will be the comparison of nominal versus real sales values, offering insights into price shifts and the implications for market resilience and growth. The primary emphasis is on the broader trends that define the industry’s past and inform its future. This review will conclude with an outlook on potential challenges and opportunities that lie ahead for Virginia’s shellfish aquaculture industry.