Feed is one of the highest cost factors in fish farming, and it has become evident that the utilization of diets for aquatic species must be as efficient as possible to reduce environmental pollution. Decades -long research has demonstrated that supplementation of aqua feeds with different nutrients, vitamins or minerals can be beneficial for fish health, growth and overall feed efficiency, especially for diets low in fishmeal . Chromium is an essential mineral for humans and certain animals, although an essentiality could not be demonstrated in fish based on the definition of an essential trace element. However, dietary supplementation with Cr in fish diets has resulted in enhanced growth performance as well as improved immune response and stress sensitivity in numerous fish species. Trivalent chromium (Cr+3 ) can support the metabolism of carbohydrates, lipids and proteins by elevating the activity of digestive enzymes and potentiating the action of insulin. Since knowledge about efficiency of organic trace mineral supplementation in different species of fish is lacking, effects of chromium- methionine (Cr-Met) complex in African catfish nutrition were evaluated. Four commercially based diets with increasing Cr-Met complex supplementation level (0, 0.2, 0.4 and 0.6 mg Cr kg-1 ) in the form of Availa®Cr 1000were fed to African catfish (Clarias gariepinus B., 1822) in quadruplicate groups at Fraunhofer IMTE in Büsum, Germany, for 84 days. Growth performance parameters (final body weight, feed conversion ratio, specific growth rate, daily feed intake, protein efficiency ratio, protein retention efficiency), health parameters (mortality, hepatosomatic index, spleen somatic index, hematocrit) and mineral retention efficiency were assessed at the end of the feeding trial. Evaluation of health parameters revealed that the applied levels of Availa-Cr 1000 inclusions are not toxic to African catfish. Moreover, s pecific growth rate (SGR) was significantly increased in fish fed diets with 0.2 mg Cr-Met kg -1 and 0.4 mg Cr-Met kg-1 supplementation in comparison with Control (Fig.1). B ased on a second-degree polynomial regression analysis, supplementation with 0.33 mg Cr-Met kg-1 was optimal in commercially-based diets for African catfish.