Soy lecithin is a valuable co-product of soy oil extraction with high content of phospholipids, which can be used as a feed additive for aquafeeds. The supplementation of phospholipids in aquafeeds may have to meet the essential requirements for physiological and metabolic function. The supplementation of soy lecithin can influence stress, improve the growth performance , and survival of several aquatic species, including channel catfish , Ictalurus punctatus. The present study is evaluating incremental doses of soy lecithin (0, 0.5, 1.0, 1.5, and 2%) in catfish diets to determine the optimal supplementation level in a plant based experimental feed . The fish were stocked in a recirculating aquaculture system and subjected to a feeding trial for 12 weeks, and this feeding trial is currently ongoing . At the end of the study production parameters will be collected and fish will be challenged by air exposure and stress markers (plasma cortisol, blood glucose, plasma osmolality, and lactate), and hematocri t will be measured. The remaining fish will be subjected to a bacterial challenge (Edwardsiella ictaluri) , to evaluate disease resistance and survival . The survival after bacterial challenge will be evaluated using the Kaplan-Meier survival test .