Natural Antioxidants were extracted from the pomegranate (Punica granatum), pineapple (Ananas comosus) and orange (Citrus sinensis) peels by methanol and their activity were evaluated by DPPH (2, 2-diphenyl-1-picrylhydrazyl) radical scavenging. The total phenolic compound (TPC) was determined by the Folin-Ciocalteu method to quantify the amounts of phenolic contents and total flavonoid content (TFC) by the Aluminium chloride colorimetric method. The Pomegranate Peel Extract exhibited total phenolic content (TPC) 221 mg/g GAE and total flavonoid content (TFC) of 194 mg QE 100g-1, the pineapple peel extract TPC of 185 mg/g GAE and TFC of 95 mg QE 100g-1 and orange peel extract TPC of 156 mg/g GAE and TFC of 82 mg QE 100g-1 respectively. The result of antioxidants activity of pomegranate peel extract showed the radical scavenging activity of 85.55% at the concentration of 0.2 µg/mL and pineapple peel extract showed the radical scavenging activity of 74.72% at the concentration of 0.4 µg/mL whereas the orange peel extract showed the radical scavenging activity 79.78 % at the concentration of 0.6 µg/mL. Among the different fruit peel extracts, pomegranates exhibited the highest antioxidant activity followed by orange and pineapple extracts. It can be concluded that the antioxidant activity, total phenolic content and total flavonoid content present in the different fruit peels can be extracted and used as natural antioxidants.