To enhance the blue economy and provide both food security and livelihood opportunities, sustainable mariculture ventures have been undertaken and supported by both government and non government actors. Commercialization of Seaweed mariculture in the South Coast of Kenya has been successfully achieved. Since 2010, commercial seaweed farming has been practised in the South coast of Kenya thereby contributing to a community-driven sustainable blue economy. The success in commercialization of seaweed farming was contributed by the high demand for seaweed products in the international market, scientific guidance into the development of the venture, good support from the county and national government and non-government actors (NGO) and a willing community of farmers in the South Coast of Kenya. This work highlights the successes achieved in commercial seaweed farming in the South Coast of Kenya. We highlight the challenges and discuss the overall contribution of commercial seaweed farming in Kenya. Further, we highlight the missteps and challenge the methodology applied by the various stakeholders in their contributions to developing seaweed commercialization. We also report on the results from analyzing sixteen years seaweed production and sales data from Kibuyuni and use the results to initiate a discussion on the need of a change in strategy by the various stakeholders.