The Glyphosate Glyphosate (N-(phosphonomethyl)glycine) is a broad-spectrum systemic herbicide and an organophosphorus compound, it kill the weed that compete with crop. It is affected the non-targeted species that leads to mass mortality of the particular species. The final discharges are in the aquatic system and finally dumped estuary area with mangrove ecosystem . For this reason, the terrible effects lead to the aquatic organisms; finally the entire aquatic biodiversity may be collapses. Bioremediation is very important technique for the current world, because the day by day discharged pollutants toxicated the biosphere and making it unsuitable for life. The chemo- remediations seem to pacify one way but aggravate on the other side. This would indulge the need for bioremediation which is eco-friendly, cost-effective and easily accessible to the environmentalist. Naturally, some micro-organisms are able to play an important role in the degradation of the toxic pollutants. Such microbes can be identified and make use of it to alleviate the emerging pollution problems. Make use of such technology in the abatement of pollution is the need of the hour. The concept of enzyme immobilization and its efficiency of working in the different area is a common phenomenon. The immobilised purified intracellular laccase on amino-functionalized silica nanoparticles have been developed and tested to determine the different environment friendly activity like decolourization of industrial toxic dyes, degradation of Glyphosate. However, the pioneer information and its implements with respect of controlling factors the survival growth and metabolism of micro-organisms in polluted environments. Although these technologies are new and upcoming. It’s application and implementation are underway with due refinement. When it is practically efficient and effective then preservation of the pristine global environ become possible. In order to reach the destination, simultaneously need of knowledge about the bioagumentaion process of microbial culture. The cost effective treatment is most important factor for its implementations and prove it be a promising technologies to consider for the remediation of environmental contaminants.