NOAA’s Office of Aquaculture (OAQ) strives to develop, support, and share the best available science for decision-making at local, regional, and national scales. Along with critical partners in other federal and state agencies, Tribes, NGOs, non-profits, industry groups, and more, OAQ uses science to inform management and decision-making for sustainable aquaculture development. Leveraging the best available science from NOAA and our partners is critical for fulfilling the strategic vision, mission, and goals of the NOAA Aquaculture Program. This presentation will outline the Aquaculture Program’s science vision and current aquaculture science portfolio, and highlight examples of how NOAA-supported science has been applied to decision-making tools.