Aquaponics integrates fish farming with soilless plant cultivation (hydroponics) in order to establish a symbiotic system where fish waste provides nutrients for plants, with bacteria facilitating the conversion of ammonia to nitrates. In contrast, hydroponics involves plant growth using nutrient-enriched water. This study aims to compare the growth rates and production of lettuce and fish within an aquaponics system. Koi fish were raised under controlled conditions, receiving a daily feed of 3% of their body weight, while lettuce seedlings were transplanted into a system utilizing reverse osmosis-treated water. Daily monitoring of total dissolved solids (TDS) and electrical conductivity (EC) ensured nutrient optimization. Water samples were tested for ammonia, nitrite, nitrate, pH, and dissolved oxygen using API strips. Preliminary results from the koi fish showed an average weight of 14.94g with a standard deviation of 4.25g across 21 samples. Lettuce growth displayed an average weights ranging from 1.95g to 34.91g, and standard deviations from 0.26 to 30.23g. These findings suggest that the aquaponic system facilitates effective nutrient transfer from the fish tank, promoting lettuce growth. Future research will compare these results to soil-grown lettuce and pond-grown fish to evaluate which method produces higher growth and yields, providing insights into sustainable agricultural practices for both leafy greens and fish production.