The use of corn-coproducts has become an efficient way to utilize ethanol co-products as concentrated sources of energy and nutrients in feeds. They are abundant in volume and processing technologies are well established, making them a good candidate to complement plant-based diets formulations. The corn fermented protein with yeast comes from a fermentation process, which increases the bioavailability of protein and reduces fiber and anti-nutritional factors (ANFs). The current study was conducted to evaluate efficacy of corn fermented protein with yeast that contains 50% of crude protein (CFP50Y), under green-water recirculation system. Four diets with 35% protein and 8% lipids extruded diets were formulated to partially reduce soybean meal as the inclusion of CFP50Y increase (0,5,10 and 20%). These diets were evaluated in 16 tanks of 800L, stocked at 34 shrimps m-2with an initial weight at 0.19 ± 0.006 g, over an experimental period of 8 weeks. At the conclusion, no significance difference was found in feed conversion ratio, growth and survival. Whole body analysis did not reveal any significant difference among diets. The outcomes from this trial indicate that CFP50Y can be used up to20% of inclusion level in the diets of pacific white shrimp without compromising growth and health.