This study was conducted to determine the growth performance of Clarias gariepinus fingerlings fed with Cocoa bean shell meal (CBS). One hundred and twenty Clarias gariepinus fingerlings were procured from a Negro farm in Ido-Ekiti, Ekiti State for the experiment. The fish were divided into ten plastic bowls (20 litres capacity) randomly at 12 fingerlings per bowl with 0%, 10%, 20%, 30%, and 40% inclusion of cocoa bean shell meal. The results for the growth parameters showed the highest mean weight gain (MWG) of 5.70g in the fish fed 40% Cocoa bean shell meal and the lowest mean weight gain of 4.44g was recorded in the fish fed 30% inclusion of cocoa bean shell meal. There was no significant difference (p>0.05) between weight recorded in all the diets. The highest standard length increase of 2.77cm was recorded in 40% inclusion of cocoa bean shell meal fed fish and the lowest value of 2.45cm was recorded in the fish fed 20% inclusion of cocoa bean shell meal with no significant difference (p>0.05) in length in all the diets. Specific Growth Rate (SGR) showed that Fish fed with 10% and 40% had the highest value of 1.0 and the lowest value of 0.8 was recorded in fish fed with 20% Cocoa bean shell meal. This study established that cocoa bean shell waste at 40% inclusion level can be incorporated into the diet of African catfish (Clarias gariepinus) without any adverse effect on growth and nutritional standard of the fish. However, further studies should still be done on the pre-conditioning and fermentation of cocoa bean shell waste for better growth, nutritional quality and also its effect on the water quality parameters of Clarias gariepinus.