Aquaponics is an activity that has been growing worldwide as a sustainable alternative for food production and practical implementation. Due to its low space demand structure, its adaptation to urban spaces is encouraged to attend the population, whose families participate in the entire process for their own consumption or sale. The tambaqui (Colossoma macropomum) is a native Brazilian species widely cultivated in aquaculture systems and has potential for aquaponics due to its robustness. The objective of this study was to develop small-scale aquaponics with a native Brazilian species, associated with the cultivation of microgreens, an agro-food trend, using arugula (Eruca sativa), and aiming at the economic viability of family production. During 70 days, the growth performance of 80 tambaqui juveniles (average initial weight = 61.88g ± 8.31g) was monitored. Two hydroponic structures, Nutrient Film Technique (NFT) and Floating Raft Technology (FRT), were tested, with four replicates. Survival of tambaquis was 100% in both treatments and the final weight of tambaquis were for NFT = 136.38g ± 35.67g and for FRT = 116.5g ± 24.63g) (Table 1). The microgreens also performed better in the NFT structures (157.38g ± 21.74g; 6.68cm ± 0.17cm) compared to the FRT (41g ± 6.18g; 4.46cm ± 0.58cm), defining the best hydroponic unit for the cultivation of E. sativa microgreens. Finally, the economic viability study was conducted considering the minimum Brazilian wage of US$ 285.66 for implementation of a homemade aquaponic system. A simulation of the sales of the final cultivation products (tambaqui and microgreens) was conducted to estimate the investment’s viability. The results indicated the possibility of operating a single system using conventional electric power, with an investment payback period of approximately 1.5 years.