In several disciplines, using in vitro models means an opportunity to do more tests in less time and cost. Within these models, the screening of molecules and functions in cells is a widely used model in biotechnology. In aquaculture, there is a challenge in improving additives and diets and understanding the mechanism of action of various compounds. Still, it is uncommon to see in vitro studies and even less in cells. These works are more concentrated in pathogen models, where cells are challenged with viruses to study the effect of molecules. However, there is little development of cell lines of biological models used in aquaculture, which makes it challenging to generate studies. However, this model has been introduced in the last few years, generating pharmacological studies, screening compounds, and describing some mechanisms. However, there is still a great challenge to achieving its use as a tool before in vivo assays, which are widely used in the industry. This review intends to show how cell lines can reduce testing time and study costs and increase the number of tests performed before developing a diet or a longer in vivo study.
Keywords
Cells, Nutrition; Production