World Aquaculture 2021

May 24 - 27, 2022

Mérida, Mexico

GENOME-WIDE IDENTIFICATION AND EXPRESSION ANALYSIS OF SIX INSULIN-LIKE PEPTIDES WITHIN Haliotis discus hannai

Young Dae Ohb*, Hyun Seok Jangb, Youn Su Chob, Han Kyu Lima,b

aDepartment of Biomedicine, Health & Life Convergence Sciences, BK21 Four, Muan-gun 58554, Jeollanam-do, Republic of Korea

bDepartment of Marine and Fisheries Resources, Mokpo National University, Muan-gun 58554, Jeollanam-do, Republic of Korea

5546688@naver.com

 

 



 Insulin is one of the essential hormones that make up the body metabolic system by converting glucose into glycogen. In animals, known as insulin-like peptides (ILPs), they are involved in growth, reproduction, and endocrine secretion. In the case of abalone, there is no report on the insulin-related system, and it will play an important role in elucidating the endocrine system of Haliotis discu s hannai . This study aims to identify six Abalone insulin-like peptides of northern abalone through transcriptome sequencing and to confirm changes after feeding through the expression levels of these peptides. Furthermore, RNA-Seq data was utilized to further explore the expression patterns of AIPs, which may help uncover vital functions of Pacific abalone. Based on the above analysis, six insulin like-peptides were analyzed each hour after feeding. this study showed a relative increase in AIP1-5 expression in hepatopancreas 3 h after feeding compared to other tissues. In most of the experimental groups, the expression levels before feeding were restored after 6 h. However, AIP6 showed the highest relative expression level after 1 h, and then decreased after 3 h of feeding. This is the first report showing the uptake of feed influence on the expression of insulin-like peptide in abalone species and it is assumed that  a  physiological regulatory mechanism using insulin-like peptides may exist in  H. discus hannai endocrine system.