In the present study, we evaluated the growth performance of whiteleg shrimp (Litopenaeus vannamei) and three halophyte plants, red orache (Atriplex hortensis) , okahijiki ( Salsola komarovii) , and minutina ( Plantago coronopus) in marine aquaponic systems with three salinity treatments (10, 15, and 20 ppt) for 4 weeks. Shrimp performed better in 15 and 20 ppt than those raised in 10 ppt. The results of final weight, WGR, SGR, and FCR for 10 ppt were 1.82±0.16 g, 79.24 ±6.09 %, 2.08±0.12 %, and 1.67±0.13, respectively; those in 15 ppt were 2.00±0.10 g, 89.88 ±2.18 %, 2.29±0.04 %, and 1.47±0.04, respectively; and those in 20 ppt were 1.99±0.07 g, 93.93±5.39 %, 2.40±0.10 %, and 1.38±0.08, respectively. On the other hand, plants had a totally opposite trend than the result of shrimp. The growth performance and nutrient content in the three halophytic plants decreased with the increasing salinity. Although plant growth was affected by the salinity, there was no significant difference between 10 and 15 ppt treatments . Given that, 15 ppt was suggested as the optimal salinity for whiteleg shrimp and the three halophytes in an indoor marine aquaponics.