Aquaculture America 2020

February 9 - 12, 2020

Honolulu, Hawaii

GENOME-WIDE IDENTIFICATION AND EXPRESSION ANALYSIS OF SIX INSULIN-LIKE PEPTIDES WITHIN PACIFIC ABALONE Haliotis discus hannai

 
Young Dae Oha , Hyo Bin Leea, Hyeon Seok Janga , Yong Bae Seob, Han Kyu Lim a,*
a Department of Marine and Fisheries Resources
Mokpo National University
Jeonnam, 58554
 Republic of Korea
Limhk@mokpo.ac.kr
 

Insulin fa mily peptide members including insulin, insulin-like growth factors (IGFs) and insulin-like peptides (ILPs) play key roles in metabolism, growth, reproduction and lifespan. Mechanisms of insulin/IGF signaling (IIS) have been well-conserved over long periods of evolutionary time. We analyzed the transcriptome sequencing of Pacific abalone (Haliotis discus hannai) and identified six novel Abalone insulin-like peptides (AIPs). We characterized the genetic features, such as the genomic organization, gene length, protein length, and sequence similarities, as well as exon-intron structures of novel AIP genes. Additionally, we utilized RNA-s eq data to further explore the expression patterns of AIPs, which may help uncover some vital functions of Pacific abalone. We performed quantitative real-time polymerase chain reactions (qPCR) in different tissues to observe their spatial expression patterns. The newly identified AIPs genes were expressed in diverse tissues. High level of AIP3 gene expression in the gill tissue and AIP2 gene expression in the mantle tissue may suggest  that these genes  function in osmoregulation, and ionic homeostasis. The genes identified in this study will lead to  the development of markers for the identification of high-growth-rate abalone and female abalone.