This speech provides some technical guideline on management and production the health and good quality of white leg shrimp (Litopeanus vannamei) postlarvae. Production in hatcheries through improved facility design and well system maintenance, water treatment and water quality management, broodstock maturation, indoor algae culture system, larval rearing and nursery, biosecurity and health management of hatchery. This speech also provides some information hint on how to standardized hatchery operating procedures and quality control interventions can be applied during hatchery production of P. vannamei postlarvae. Expected to facilitate the efforts of hatchery operators to produce good quality, disease-free, healthy P. vannamei postlarvae, thus improving overall production and the sustainability of white shrimp aquaculture.