Vibriosis is a major threat to aquaculture industry due to its devastating nature. Although, various controlling measures have been developed for human vibrio infections, adaptability of the same to aquaculture is questionable due to restriction of using antibiotics in aquaculture. Hence, development of alternative approach gains its momentum. In the present study, the aqueous garlic extract was characterized as an alternative prophylactic measure for shrimp vibriosis. The study result revealed that the garlic extract has an antivibriosis activity by its increasing dose dependent zone of inhibition. Further study is being carried out t to prove its potential effect on other pathogenic Vibrio spp., such as V. parahemolyticus and , V. cholerae.